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-Why PrecISE? Better ways to treat severe asthma

-Photo of a PrecISE Participant Advisory Council (PAC) member.
What is Severe Asthma?
Asthma is a long-lasting disease. It affects the airways that carry air in and out of the lungs. The airways can react to such things as dust, pollen, chemicals, or bacteria. Some symptoms of asthma are wheezing, coughing, chest tightness, and trouble breathing. Most people with asthma can control their symptoms with medicine. They can still do their daily activities.
About 10-15% of people with asthma have severe asthma. There are different types of severe asthma. It can start in childhood or later in life. Medicines for asthma that are available right now often don’t work well for people with severe asthma. This disease can make their lives very difficult.

What is PrecISE?
PrecISE is a research study to understand how to treat different types of severe asthma. PrecISE will study adults and adolescents with severe asthma. We are looking for people who have asthma attacks or frequent asthma symptoms. Everyone in the study will receive medicine that is based on the type of severe asthma they have.
This study is sponsored by the U.S. National Heart, Lung, and Blood Institute.

How PrecISE is Different from Other Severe Asthma Studies
Many studies look only at the patient’s symptoms or lung function for choosing a medicine. But people with severe asthma can be very different from each other. They may have the same symptoms, but different things can be happening in their bodies that cause the same symptoms. This means that the same medicine might not work the same way in different people, even if they have the same symptoms. This is one reason that severe asthma is so hard to treat.
PrecISE has two goals: 1) Research how to more easily identify some of the types of severe asthma. 2) Research treatments for the types of severe asthma being studied in PrecISE.

News and Research

Moderate to Severe Asthma: A Podcast Series
A limited podcast series is now available that takes a deep dive into the diagnosis, treatment, and ongoing care of patients with moderate to severe asthma. Produced by Medscape, the “InDiscussion: Moderate to Severe Asthma” podcast series is an in-depth interview style-look at the field of asthma.

Severe Asthma
The PrecISE Clinical Trial, Time Commitment, New Type of Asthma Study, Compensation, Enroll.

Publications Update - The Study's Design
Latest publications - see the list here.