Many studies characterize participants based on their symptoms and/or their lung function, and use a treatment based on those symptoms. However, people with asthma may have similar symptoms, but different processes in their bodies that cause those symptoms. Since we now know that the symptoms of asthma can be caused in different ways, we also know that patients with similar symptoms do not respond in the same way to many treatments. This is part of the reason severe asthma is difficult to treat.
PrecISE has two goals: 1) Research how to more easily identify some of the types of severe asthma. 2) Research treatments for the types of severe asthma being studied in PrecISE.